It is commonly thought that people who insist on shoes-off in their homes are neat freaks who are obsessed with keeping their homes clean and tidy.
I dare say that there are some people who prefer shoes-off who are genuine neat freaks. And those who are Obsessive-Compulsive about cleanliness may well be among the shoes-off community.
Of course this is culturally relative. In Japan it is thought that money is dirty and unhygeinic because it is handled by untold numbers of people. Japanese people also regard any objects placed in bathrooms, such as books or ornaments to be 'dirty'. A person in a western society who held such attitudes would almost certainly be regarded as Obsessive-Compulsive.
I have known a number of people who really were excessive in their desire to keep their homes clean. Interestingly, these people did not require visitors to remove their shoes. I suspect that they probably spent so much time in cleaning their homes that they were happy to waste time cleaning up after their visitors.
Many people who keep their homes shoe-free are not domestic goddesses who like nothing better than spending whole days doing spring cleaning. Rather, they are busy working people who have far better things to do. They do not want to clean up for the sake of it, but they know that living in a clean environment is healthier and far more pleasent. Knowing that time is precious they would rather keep the mess to the minimum and spend as little time as possible cleaning up after their visitors. Prevention is better than cure.
Nobody needs a house that is spotless, but it is pointless to allow dirt and dust to accumulate when it could easily be kept out by leaving shoes at the door. A floor is meant to be walked upon, but that does not mean that one should not reduce wear and tear and save time and money.